Australian National Phenome Centre 

The Australian National Phenome Centre (ANPC), located in Western Australia, is an international research node dedicated to developing and delivering metabolic phenotyping services to benefit the global population. The ANPC is the nation’s first phenome hub. It is affiliated with the International Phenome Centre Network (IPCN) and shares an interest in building a global infrastructure around harmonised research information, data, methods and technologies. A key part of the initiative is the harmonisation of instruments between the network members, ensuring that samples can be run anywhere in the world and the results will be the same. The network will enable database sharing and big data mining with other health and research institutions.

It’s development allows Australian scientists to be part of the global research effort working to transform health and improve disease prevention, detection and treatment. Large scale metabolic phenotyping data will greatly advance precision medicine by enabling better understanding of the dynamic interactions between our genes, environments, microbiomes, diets and lifestyles across populations.

Services and Facilities

The WA based Centre offers researchers a high-throughput capability in targeted and exploratory metabolic phenotyping. It enables analysis of patient and population-based samples for the purpose of novel biomarker, diagnostic and prognostic marker discovery.

The ANPC aims to deliver a world-class competency in metabolic phenotyping research in association with local and international research institutions, hospitals and industry. The WA based Centre will be the training hub for metabolic phenotyping in the Southern Hemisphere. The centre provides expertise on a wide range of issues, including sample collection, sample storage, sample preparation, sample running, and data analysis.

The ANPC is a core platform of the WAHTN. It involves collaborations between all WAHTN partners, including the five Universities in WA, the WA health research institutes, and the WA health department.

The ANPC is based at the Harry Perkins Institute for Medical Research South at the Fiona Stanley Hospital campus (see image below).

Partner Centres and International Collaborations

The centre has been established as part of an international initiative led by the International Phenome Centre Network (IPCN) to develop and perform large-scale metabolic phenotyping of the human population for stratified medicine. The IPCN was officially launched at the World Innovation Summit for Health, November 2016. Other partners of the IPCN are located in Canada, China, Japan, Singapore, Taiwan, the United States and the United Kingdom.

Partner Centres of the International Phenome Centre Network (IPCN)

International Phenome Centre Network Partners

Australian National Phenome Centre - Murdoch University

MRC-NIHR National Phenome Centre - Imperial College London, UK

Imperial International Phenome Training Centre - Imperial College London, UK

Clinical Phenotyping Centre - Imperial College London, UK

Phenome Centre Birmingham - University of Birmingham, UK

Birmingham Metabolomics Training Centre - University of Birmingham, UK

Singapore Phenome Centre - Nanyang Technological University, Singapore

Partners of the Australian National Phenome Centre 

Murdoch University, WA, was awarded funding to establish the Australian National Phenome Centre in November 2016. The funding initiative is the result of a consortium of all five Western Australian universities: Murdoch University; Curtin University; the University of Western Australia; Edith Cowan University and The University of Notre Dame Australia. Partners also include the Telethon Kids Institute, the Harry Perkins Medical Research Institute, the Pawsey Supercomputing Centre in Perth, and the EPICentre at the University of New South Wales.

Associate Professor Robert Trengove, from Murdoch University’s Separation Science Laboratory, is Chief Investigator on the project.

 

For further information, please see link - Media Release - WAHTN, 03/11/2016